Description of REST APIs that can be used for searching Clinfx Database. All the server repsonses are in JSON format.
Beta
http://clinfx.wiley.com/aaccweb/aacc/search
This section has APIs to list the set of available tests, factors and ICDs in the Clinfx database. There is no authentication scheme necessary for these APIs.
http://clinfx.wiley.com/aaccweb/aacc/search/
http://clinfx.wiley.com/aaccweb/aacc/search/test/?test={searchterm}
http://clinfx.wiley.com/aaccweb/aacc/search/test/?test=inulin
{ tests: [2] 0: { id: 2527 name: "Inulin" }- 1: { id: 2528 name: "Inulin Clearance" } }The JSON response from the server returns the details of the two tests having the matching term "inulin" in it. The tests parameter also shows the total number of matches found (in the above example =2).
http://clinfx.wiley.com/aaccweb/aacc/search/factor/?factor={searchterm}
http://clinfx.wiley.com/aaccweb/aacc/search/factor/?factor=iron
{ factors: [10] 0: { id: 2777 factorname: "Iron Sorbitex" icd9: null product: 1 }- 1: { id: 2778 factorname: "Iron-Protein-Succinylate" icd9: null product: 1 }- 2: { id: 2772 factorname: "Iron" icd9: null product: 1 }- 3: { id: 2773 factorname: "Iron Deficiency Anemia" icd9: 10585 product: 3 }- 4: { id: 2775 factorname: "Iron Dextran" icd9: null product: 1 }- 5: { id: 2776 factorname: "Iron Overload" icd9: 9935 product: 3 }- 6: { id: 4357 factorname: "Saccharated Iron Oxide" icd9: null product: 1 }- 7: { id: 7020 factorname: "Iron-deficient Diet" icd9: null product: 2 }- 8: { id: 7872 factorname: "Iron Sucrose" icd9: null product: 1 }- 9: { id: 7873 factorname: "Iron Gluconate" icd9: null product: 1 } }The response from the server returns the details of the 10 matching factors having the term "iron" in it. The id parameter represents a unique id number. The factorname represents complete name of the matching factor. The icd9 provides the ICD 9 value for the corresponding factor, while the product parameter is irrelevant in the current context.
http://clinfx.wiley.com/aaccweb/aacc/search/icd/?icd={searchterm}
http://clinfx.wiley.com/aaccweb/aacc/search/icd/?icd=272
{ icd9s: [10] 0: { id: 9572 code: "272.0" }- 1: { id: 9587 code: "272.1" }- 2: { id: 9610 code: "272.2" }- 3: { id: 9627 code: "272.3" }- 4: { id: 9640 code: "272.4" }- 5: { id: 9660 code: "272.5" }- 6: { id: 9669 code: "272.6" }- 7: { id: 9751 code: "272.7" }- 8: { id: 9800 code: "272.8" }- 9: { id: 9808 code: "272.9" } }The JSON response from the server returns the details of the 10 matching ICD 9 values for search term "272". The icd9s parameter also shows the total number of matches found (in the above example =10).The parameter code has the respective complete ICD 9 value.
This Search API looks for interactions in the clinfx database based on a various parameters like "test" name , "factor" name, "factortype", "mechanism", "icd" or "explanation". A combination of these various parameters can be entered for searching an interaction. Apart from these, a set of authentication parameters are also needed, which are "userid", "timestamp", "apikey" and "signature".
http://clinfx.wiley.com/aaccweb/aacc/search/
http://clinfx.wiley.com/aaccweb/aacc/search/authenticate/?userid={emailid}
http://clinfx.wiley.com/aaccweb/aacc/search/authenticate/[email protected]
{ apikey: "f5e4014085ede42a710841457" }The above response shows a valid apikey is returned from the server. For an invalid user, a null value is returned. The search API uses this "apikey" value as one of its input parameters.
http://clinfx.wiley.com/aaccweb/aacc/search/?test={testname}&userid={emailid}×tamp={timestamp}&apikey={apikey}&signature={signature}
http://clinfx.wiley.com/aaccweb/aacc/search/?test=inulin&[email protected]×tamp=1408542619&apikey=f5e4014085ede42a710841457&signature=9938da2c01e61d514675bec7025b558b177001e1
{ total: 36 results: { Acetazolamide: 1 Amiloride: 2 Aspirin: 2 Bilirubin: 1 Bopindolol: 2 Bumetanide: 1 Creatinine: 1 Cyclosporine: 2 Cyclosporine A: 1 Dextran: 1 Diazoxide: 1 Diltiazem: 1 Dopamine: 1 Etodolac: 1 Felodipine: 1 Food Ingestion: 2 Fructose: 2 Furosemide: 1 Glucose: 3 Gout: 2 Hemoglobin: 1 Hepatolenticular Degeneration: 1 High Sodium Diet: 1 Hydralazine: 1 Levodopa: 1 Mannose: 2 Methylprednisolone: 1 Nifedipine: 1 Old Age: 1 Phloridzin: 1 Pregnancy: 1 Renovascular Hypertension: 1 Systemic Lupus Erythematosus: 1 Tertatolol: 1 Triglycerides: 1 Urea: 1 } }The response shows a total parameter with 36 factors returned. The results parameter shows the name of the factors and for each factor the count of number of interactions found. The following java code can be used for calculating the signature incase a java based client is used for making the REST calls. The Apache Commons Codec library link is also used in computing the signature.
import java.io.UnsupportedEncodingException; import java.security.GeneralSecurityException; import javax.crypto.Mac; import javax.crypto.spec.SecretKeySpec; import org.apache.commons.codec.binary.Hex; public class Hmac { public String computeSignature(final String baseString, final String key) throws GeneralSecurityException, UnsupportedEncodingException { final SecretKeySpec secretKey = new SecretKeySpec(key.getBytes(), "HmacSHA1"); final Mac mac = Mac.getInstance("HmacSHA1"); mac.init(secretKey); byte[] rawHmac = mac.doFinal(baseString.getBytes()); byte[] hexBytes = new Hex().encode(rawHmac); return new String(hexBytes, "UTF-8"); } }Calculating the signature (HMAC SHA1 hash) requires two input parameters for the hashing function. One is the "baseString" and another being the "key". The "key" is a sceret key that will be communicated by Wiley, individually to the interested customers, who want to use the Clinfx APIs. The "baseString" is a combination of "userid"+"apikey"+"timestamp". "userid" is same as email id. Timestamp is whatever timestamp that can be generated at the client side. The "timestamp" is more or less used as a parameter to enable generating different signature values with each REST call. Hence it's irrelevant from which reference date the timestamp is calculated (but it should be number). The "apikey" is obtained as previously explained. Same "apikey" can be used for all searches for a span of 60 minutes after which it has to be re-generated.
http://clinfx.wiley.com/aaccweb/aacc/search/?test=inulin&[email protected]×tamp=1408542619&apikey=f5e4014085ede42a710841457&signature=9938da2c01e61d514675bec7025b558b177001e1
http://clinfx.wiley.com/aaccweb/aacc/search/?factor={factorname}&userid={emailid}×tamp={timestamp}&apikey={apikey}&signature={signature}
http://clinfx.wiley.com/aaccweb/aacc/search/?factor=acetone&[email protected]×tamp=1409218028&apikey=3b07e14092f16ed2a25117966&signature=b57495e1e809b0c4882f3dba8f4ffb133bc0a3fc
{ total: 26 results: { 17-Hydroxycorticosteroids: 1 17-Ketogenic Steroids: 1 17-Ketosteroids: 1 Acetonitrile: 1 Albumin: 3 Ammonia: 1 Amphetamine: 1 Barbiturate: 1 Benzoylecgonine: 1 Bogen Test: 1 Cannabinoids: 1 Creatinine: 13 Estriol: 1 Ethanol: 5 Ethylene Glycol: 1 Glucose: 1 Ketones: 1 Lactate: 1 Methadone: 1 Opiates: 1 Osmolal Gap: 1 Phencyclidine: 1 Propoxyphene: 1 Urea Nitrogen: 2 Urobilinogen: 1 pH: 1 } }The response shows a total parameter with 26 tests returned. The results parameter shows the name of the tests and for each test the count of number of interactions found. The signature is computed as previously explained.
http://clinfx.wiley.com/aaccweb/aacc/search/?test={testname}&factor={factorname}&start={rownumber}&userid={emailid}×tamp={timestamp}&apikey={apikey}&signature={signature}
http://clinfx.wiley.com/aaccweb/aacc/search/?test=bilirubin&factor=leptospirosis&start=0&[email protected]×tamp=1409218028&apikey=3b07e14092f16ed2a25117966&signature=b57495e1e809b0c4882f3dba8f4ffb133bc0a3fc
{ results: [9] 0: { id: 47402 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Jaundice may appear at the end of the 1st week of fever. Liver tests show hepatic decompensation of the intrahepatic type" refid: 18497 referencetitle: "Communicable and Infectious Diseases" journalauthors: "Top FH Wehrele PF (eds)" publication: "7th edition" publisher: "St Louis MO, CV Mosby" journalyear: 1972 journalpages: "" journalvolume: null journalissn: null }- 1: { id: 47417 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "May reach 65 mg/dL but is < 20 mg/dL in 66% of patients" refid: 1244 referencetitle: "Textbook of Medicine. 14th edition" journalauthors: "Beeson-McDermott" publication: "Unknown" publisher: "Philadelphia PA, WB Saunders" journalyear: 1975 journalpages: "" journalvolume: null journalissn: "" }- 2: { id: 47431 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Elevated values found in patients without clinically evident liver disease" refid: 7263 referencetitle: "The Laboratory in Clinical Medicine" journalauthors: "Halsted JA" publication: "Unknown" publisher: "Philadelphia PA, WB Saunders" journalyear: 1976 journalpages: "" journalvolume: null journalissn: "" }- 3: { id: 47444 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Increased in 50% of the patients" refid: 19391 referencetitle: "" journalauthors: "Wallach J" publication: "Interpretation of Diagnostic Tests, 3rd edition" publisher: "Boston MA, Little Brown and Co" journalyear: 1978 journalpages: "" journalvolume: null journalissn: null }- 4: { id: 53150 test: "Bilirubin, Direct" testsynonyms: [1] 0: "Direct Bilirubin" - testterms: [1] 0: "Conjugated Bilirubin" - factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Hyperbilirubinemia, which is predominantly conjugated (direct), may reach 65 mg/dL but is < 20 mg/dL in 66% of patients" refid: 1244 referencetitle: "Textbook of Medicine. 14th edition" journalauthors: "Beeson-McDermott" publication: "Unknown" publisher: "Philadelphia PA, WB Saunders" journalyear: 1975 journalpages: "" journalvolume: null journalissn: "" }- 5: { id: 109781 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "May be associated with profound jaundice" refid: 51147 referencetitle: "Liver disease and Laboratory Medicine" journalauthors: "McFarlane I Bomford A Sherwood R eda" publication: "Unknown" publisher: "ACB Venture Publications, London" journalyear: 2000 journalpages: "" journalvolume: null journalissn: "" }- 6: { id: 122889 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Observed with hepatocellular dysfunction caused by leptospirosis." refid: 51541 referencetitle: "Jaundice" journalauthors: "McKnight JT Jones JE" publication: "American family physician." publisher: "" journalyear: 1992 journalpages: "1139-1148" journalvolume: "45" journalissn: "0002-838X" }- 7: { id: 122954 test: "Bilirubin, Conjugated" testsynonyms: [1] 0: "Conjugated Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Observed with hepatocellular dysfunction caused by leptospirosis." refid: 51541 referencetitle: "Jaundice" journalauthors: "McKnight JT Jones JE" publication: "American family physician." publisher: "" journalyear: 1992 journalpages: "1139-1148" journalvolume: "45" journalissn: "0002-838X" }- 8: { id: 139360 test: "Bilirubin, Total" testsynonyms: [2] 0: "Bilirubin" 1: "Total Bilirubin" - testterms: null factor: "Leptospirosis" factorsynonyms: [2] 0: "Leptospirosis Icterohemorrhagica" 1: "Weil's Disease" - factorterms: null icd9cm: "100.9" specimen: "Serum" effect: "Increase" mechanism: "Physiological" explanation: "Leptospirosis infections may present as acute hepatic injury." refid: 52274 referencetitle: "Diagnosis and monitoring of hepatic injury. II. Recommendations for use of laboratory tests in screening, diagnosis, and monitoring" journalauthors: "Dufour DR Lott JA Nolte FS Gretch DR Koff RS Seeff LB" publication: "Clinical chemistry." publisher: "" journalyear: 2000 journalpages: "2050-2068" journalvolume: "46" journalissn: "0009-9147" }- - total: 9 start: 0 rows: 10 }The response shows a total parameter with 9 interactions returned. The results parameter shows the details for each interaction. For each interatcion the id is a unique row id similar to a primary key. The test denotes the complete name of the test. testsynonyms are all the synonyms for the returned test. It can have a single value or null value or multiple synonyms. testterms denote the other similar tests which can be related to the returned test name. factor denotes the full name of the factor in the database. factorsynonyms denotes the synonyms for the factor. factorterms denotes the the other similar factors which can be related to the returned factor. icd9cm denotes the ICD 9 value for the factor name. specimen, mechanism, effect and explanation have their respesctive meaning for an interaction. refid, referencetitle, journalauthors , publication, publisher, journalyear, journalpages, journalvolume and journalissn are all relevant information regarding, from which journal the reference to this particular interaction is taken by the authors of Clinfx. if total is greater than 10, the next set of interactions can be obtained by providing start=10 in the REST call, while keeping other parameters the same.
http://clinfx.wiley.com/aaccweb/aacc/search/?icd={icd9value}&start={rownumber}&userid={emailid}×tamp={timestamp}&apikey={apikey}&signature={signature}
http://clinfx.wiley.com/aaccweb/aacc/search/?icd=200&start=0&[email protected]×tamp=1409218028&apikey=3b07e14092f16ed2a25117966&signature=b57495e1e809b0c4882f3dba8f4ffb133bc0a3fc
{ results: [10] 0: { id: 3509 test: "Immunoglobulin G" testsynonyms: [1] 0: "IgG" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Poorly-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "No Effect" mechanism: "Physiological" explanation: "Mean concentration in patients with poorly-differentiated lymphocytic lymphoma not significantly changed" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 1: { id: 3547 test: "Immunoglobulin D" testsynonyms: [1] 0: "IgD" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Poorly-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "No Effect" mechanism: "Physiological" explanation: "Mean concentration in patients with poorly-differentiated lymphocytic lymphoma not significantly changed" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 2: { id: 3555 test: "Immunoglobulin E" testsynonyms: [1] 0: "IgE" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Poorly-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "No Effect" mechanism: "Physiological" explanation: "Mean concentration in patients with poorly-differentiated lymphocytic lymphoma not significantly changed" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 3: { id: 3564 test: "Immunoglobulin M" testsynonyms: [1] 0: "IgM" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Poorly-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "No Effect" mechanism: "Physiological" explanation: "Mean concentration in patients with poorly-differentiated lymphocytic lymphoma not significantly changed" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 4: { id: 3539 test: "Immunoglobulin A" testsynonyms: [1] 0: "IgA" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Poorly-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "Decrease" mechanism: "Physiological" explanation: "Mean concentration in patients with poorly-differentiated lymphocytic lymphoma significantly reduced" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 5: { id: 6298 test: "Immunoglobulin G" testsynonyms: [1] 0: "IgG" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Well-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "Decrease" mechanism: "Physiological" explanation: "Mean concentration in patients with well-differentiated lymphocytic lymphoma significantly reduced" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 6: { id: 6319 test: "Immunoglobulin M" testsynonyms: [1] 0: "IgM" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Well-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "Decrease" mechanism: "Physiological" explanation: "Mean concentration in patients with well-differentiated lymphocytic lymphoma significantly reduced" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 7: { id: 6307 test: "Immunoglobulin A" testsynonyms: [1] 0: "IgA" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Well-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "Decrease" mechanism: "Physiological" explanation: "Mean concentration in patients with well-differentiated lymphocytic lymphoma significantly reduced" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 8: { id: 6439 test: "Immunoglobulin E" testsynonyms: [1] 0: "IgE" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Well-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "Decrease" mechanism: "Physiological" explanation: "Mean concentration in patients with well-differentiated lymphocytic lymphoma significantly reduced" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- 9: { id: 6430 test: "Immunoglobulin D" testsynonyms: [1] 0: "IgD" - testterms: [1] 0: "Immunoglobulins" - factor: "Lymphocytic Lymphoma, Well-differentiated" factorsynonyms: null factorterms: null icd9cm: "200.1" specimen: "Serum" effect: "No Effect" mechanism: "Physiological" explanation: "Mean concentration in patients with well-differentiated lymphocytic lymphoma not significantly changed" refid: 50293 referencetitle: "Biochemical tests in the diagnosis, classification, and management of patients with malignant lymphoma and leukemia" journalauthors: "Goldberg DM Brown D" publication: "Clinica chimica acta; international journal of clinical chemistry." publisher: null journalyear: 1987 journalpages: "1-76" journalvolume: "169" journalissn: "0009-8981" }- - total: 15 start: 0 rows: 10 }The response shows a total parameter with 15 interactions found. The results parameter shows the details for each interaction. The next set of interactions can be obtained by providing start=10 in the REST call, while keeping other parameters the same.
http://clinfx.wiley.com/aaccweb/aacc/search/?test={testname}&factor={factorname}&factortype={factorType}&mechanism={mechanism}&icd={icd9value}&start={rownumber}&userid={emailid}×tamp={timestamp}&apikey={apikey}&signature={signature}
http://clinfx.wiley.com/aaccweb/aacc/search/?test=insulin&factortype=drug&mechanism=analytical&start=0&[email protected]×tamp=1409218028&apikey=3b07e14092f16ed2a25117966&signature=b57495e1e809b0c4882f3dba8f4ffb133bc0a3fc